Genomic signatures and antiviral drug susceptibility profile of A(H1N1)pdm09
نویسندگان
چکیده
منابع مشابه
Genomic signatures and antiviral drug susceptibility profile of A(H1N1)pdm09.
BACKGROUND Genetic changes in influenza surface and internal genes can alter viral fitness and virulence. Mutation trend analysis and antiviral drug susceptibility profiling of A(H1N1)pdm09 viruses is essential for risk assessment of emergent strains and disease management. OBJECTIVE To profile genomic signatures and antiviral drug resistance of A(H1N1)pdm09 viruses and to discuss the potenti...
متن کاملcomparative dna interaction studies of antiviral drug, zidovudine and its complex using different instrumental methods
هدف از این مطالعه بررسی امکان استفاده از داروهای شناخته شده در درمان سایر بیماریها به عنوان داروهای ضد سرطان است. همچنین با استفاده از این داروها در ساختمان کمپلکس فلز می توان شاخص های دارویی بدست آمده را بررسی نمود. داروی ضد ویروس ایدز(hiv)به نام زیدوودین(azt)انتخاب و.کمپلکس.محلول.در.آب[pt(azt)2]cl2سنتزو به روشهای مختلف فیزیکی و شیمیایی شناسایی گردید. بر هم کنش مقایسه ای این دارو و کمپلکس پلا...
15 صفحه اولAntiviral Profile of Brown and Red Seaweed Polysaccharides Against Hepatitis C Virus
Hepatitis C virus (HCV) has infected 3% of the population worldwide and 20% of the population in Egypt. HCV infection can lead to hepatocellular carcinoma and death. The presently available treatment with interferon plus ribavirin, has limited benefits due to adverse side effects. Seaweeds have become a major source of new compounds to treat viral diseases. This work aimed to study the effect o...
متن کاملMolecular signatures of basal cell carcinoma susceptibility and pathogenesis: a genomic approach.
Gene expression profiling can be useful for phenotypic classification, investigation of functional pathways, and to facilitate the search for disease risk genes through the integration of transcriptional data with available genomic information. To enhance our understanding of the genetic and molecular basis of basal cell carcinoma (BCC) we performed global gene expression analysis to generate a...
متن کاملAntiviral diabetes susceptibility gene
The authors previously showed that an A/G splicing site single nucleotide polymorphism in the OAS1 gene is strongly correlated to the basal activity of the antiviral oligoadenylate synthetase (OAS). Basal activity was highest in individuals with the GG genotype and lowest in those with the AA genotype. In the present study, OAS1 GG and GA genotypes were increased in type 1 diabetic individuals ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Clinical Virology
سال: 2012
ISSN: 1386-6532
DOI: 10.1016/j.jcv.2011.11.002